Ladbrokes is regulated by Gibraltar and powered by Microgaming casino games. Both Gibraltar and Microgaming do not accept citizens from the United States of America.
I sent an email to the Ladbrokes support to get a clear explanation. Here is their answer :
Unfortunately at present we are unable to accept online registrations from customers who are resident in the USA or its territories.
Ladbrokes have taken extensive legal advice regarding the legality of providing online gaming services to account registrations originating from the USA. Whilst the matter is - unsurprisingly - not entirely clearcut, the current consensus view is that telephone and internet sports betting is illegal under existing federal (and most state) legislation and gaming may be illegal (although the latter is subject to some debate by lawyers and other interested parties it is certainly the view that the Department of Justice take).
If this were to be the case, we would commit a criminal offence should we accept bets over the telephone or internet. This is not a risk that, for a number of corporate reasons - including the fact we have business interests and assets in the US, the very high costs of litigation and the fact that we are a very well known brand and therefore possibly more likely to be used as an example - we are currently prepared to take.
We hope this clarifies the matter for you and should the legal situation change then we would be happy to accept online transactions from customers such as yourself.
As part of the US gambling law, Ladbrokes preferred to step back from the US Markets. However, some online casinos still continue to accept US citizens. Check our top 3 US Casinos.
Technically, you could play to Ladbrokes if you signed up from abroad. For instance if you are in vacation in Colombia or in Argentina, you could play to Ladbrokes while you drink your Cuba Libre. However, you should not use a US address and an american credit card (from Bank of America for instance).
This is the same problem as "signing-up from abroad". You could use a VPN to play to Ladbrokes, but you would need to have a real address outside of the US (with electricity bill at your name for instance). If you have an aunt abroad, for instance in the Russia, it could work. Otherwise, in case you win a $7,000,000 jackpot, Ladbrokes could block your funds..
We know that Bovada is currently accepting US citizens. It is powered by Top Game software and offers a nice welcome bonus.